Ming Dao, Ph.D.

Principal Research Scientist, Nanomechanics Laboratory @ MIT
Principal Investigator, Infectious Disease IRG @ SMART Center
Adjunct Professor, CAMP-Nano @ Xi'an Jiaotong University

Office: Room 8-139, Email: mingdao@mit.edu,
Department of Materials Science and Engineering
Massachusetts Institute of Technology
77 Massachusetts Avenue, Cambridge, MA 02139

Experiences

• Principal Research Scientist, Dept of Materials Sci & Eng, MIT, Feb. 2011 - present
• Adjunct Professor, CAMP-Nano, Xi'an Jiaotong University, Oct. 2011 - present
• Principal Investigator, Dept of Materials Sci & Eng, MIT, Oct. 2010 - present
• Principal Investigator, Infectious Disease Interdisciplinary Research Group, SMART Center, Oct. 2010 - present
• Executive Director, Lab for Micro- & Nano-Mechanics (Nanomechanics Laboratory), MIT, Oct. 2007 - Oct. 2010
• Research Scientist, Dept of Materials Sci & Eng, MIT, Mar. 2000 - Jan. 2011
• Consultant and Visiting Scientist, Alcoa Technical Center, Pennsylvania, Jan. 2000 - 2004
• Review Engineer/Senior Support Engineer, ABAQUS, Inc., Aug. 1998 - Jan. 2000
• Project Scientist and Lecturer, Univ of California at San Diego, Dept of Structural Eng., Mar. 1998 - Aug. 1998
• Engineering Consultant, Trans Science Corporation, San Diego, California, Dec. 1996 - Aug. 1998
• Reviewer for Science, Progress in Materials Science, Blood, Physical Review E, Physical Review Letters, Advanced Functional Materials, Biophysical J, J Mech Phys Solids, Acta Mater, Acta Biomater, Scientific Reports, Scripta Mater, Phil Mag, Phil Mag Lett, J Appl Phys, Int'l J Solids Structures, J Mater Res, J Mater Sci, Composites Sci & Tech, Mech Mater, Int J Plasticity, Mat Sci & Eng A, J Metastable & Nanocrystalline Mater
• Reviewer/Panelist for Research Proposals submitted to US National Science Foundation (NSF), US Department of Energy (DOE), Swiss National Science Foundation (SNSF), Israel Science Foundation (ISF), Science Foundation Ireland (SFI), The Foundation for Polish Science (FNP), and Georgian Shota Rustaveli National Science Foundation (SRNSF)

Current Research Interests

• Biomechanics and Biophysics of the Cell
• Malaria
• Nanoscale Properties of Biological Materials
• Nanostructured or Amorphous Materials
• Nano-Indentation and Micro-Indentation
• Surfaces and Thin Films
• Functionally Graded Materials

Selected Publications

P.A. Carvalho, M. Diez-Silva, H. Chen, M. Dao and S. Suresh, "Cytoadherence of erythrocytes invaded by Plasmodium falciparum: Quantitative contact-probing of a human malaria receptor," Acta Biomaterialia, 2013, in press.

S. Huang, A. Undisz, M. Diez-Silva, H. Bow, M. Dao and J. Han, "Dynamic deformability of Plasmodium falciparum-infected erythrocytes exposed to artesunate in vitro," Integrative Biology, 5 (2013) 414-422.

Y. Zhang, H. Zhu, M. Fujiwara, J. Xu and M. Dao, "Low Temperature Creep of SnPb and SnAgCu Solder Alloys and Reliability Prediction in Electronic Packaging Modules," Scripta Materialia, 68 (2013) 607-610.

P. Li, Z.S. Stratton, M. Dao, J. Ritz and T.J. Huang, "Probing circulating tumor cells in microfluidics," Lab on a Chip, 13 (2013) 602-609. (See Lab on a Chip Blog about this article.)

D. Carnelli, P. Vena, M. Dao, C. Ortiz and R. Contro, "Orientation and Size Dependent Mechanical Modulation within Individual Secondary Osteons in Cortical Bone Tissue," J. R. Soc. Interface, 10 (2013) 20120953.

M. Diez-Silva, Y.-K. Park, S. Huang, H. Bow, O. Mercereau-Puijalon, G. Deplaine, C. Lavazec, S. Perrot, S. Bonnefoy, M.S. Feld, J. Han, M. Dao and S. Suresh, "Pf155/RESA protein influences the dynamic microcirculatory behavior of ring-stage Plasmodium falciparum infected red blood cells," Scientific Reports (Nature.com/srep), 2 (2012) 614. (See MIT News Report, ScienceDaily News.)

H.-S. Byun, T.R. Hillman, J.M. Higgins, M. Diez-Silva, Z. Peng, M. Dao, R.R. Dasari, S. Suresh and Y.-K. Park, "Optical measurement of biomechanical properties of individual erythrocytes from a sickle cell patient," Acta Biomaterialia, 8 (2012) 4130-4138. (See supplementary materials.)

Y. Zhang, H. Yao, C. Ortiz, J. Xu and M. Dao, "Bio-inspired interfacial strengthening strategy through geometrically interlocking designs," J. Mech. Behav. Biomed. Mater., 15 (2012) 70-77.

A. Jerusalem and M. Dao, "Continuum modeling of neuronal cell under blast loading," Acta Biomaterialia, 8 (2012) 3360-3371. (See supplementary materials.)

M. Aingaran, R. Zhang, S.K.Y. Law, Z. Peng, A. Undisz, E. Meyer, M. Diez-Silva, T.A. Burke, T. Spielmann, C.-T. Lim, S. Suresh, M. Dao and M. Marti, "Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum," Cellular Microbiology , 14 (2012) 983-993. (July 2012 Editor's Choice) (See supplementary materials.)

A. Singh, N.R. Tao, M. Dao and S. Suresh, "Repeated frictional sliding properties of copper containing nanoscale twins," Scripta Materialia (Viewpoint Paper), 66 (2012) 849-853.

J.F. Vicente, Y. Zhang, M. Dao, J. Lu, F. Galvez and A. Jerusalem, "Ballistic performance of nanocrystalline and nanotwinned ultrafine crystal steel," Acta Materialia, 60 (2012) 1353-1367.

P. Gu, B.K. Kad and M. Dao, "Revisiting the intra-granular dislocation extension model for flow stress in nanocrystalline metals," Philos. Mag. Lett., 92 (2012) 111-121.

A. Singh, M. Dao, L. Lu and S. Suresh, "Deformation, structural changes and damage evolution in nanotwinned copper under repeated frictional contact sliding," Acta Materialia, 59 (2011) 7311-7324.

P. Gu, M. Dao, R.J. Asaro and S. Suresh, "A unified mechanistic model for size-dependent deformation in nanocrystalline and nanotwinned metals," Acta Materialia, 59 (2011) 6861-6868.

L. Zhu, H. Ruan, X. Li, M. Dao, H. Gao and J. Lu, "Modeling grain size dependent optimal twin spacing for achieving ultimate high strength and related high ductility in nanotwinned metals," Acta Materialia, 59 (2011) 5544-5557.

R. Chandramohanadas, Y.-K. Park, L. Lui, A. Li, D. Quinn, K. Liew, M. Diez-Silva, Y. Sung, M. Dao, C.-T. Lim, P.R. Preiser and S. Suresh, "Biophysics of Malarial Parasite Exit from Infected Erythrocytes," PLoS ONE, 6 (2011) e20869. (See supplementary materials.)

H. Bow, I.V. Pivkin, M. Diez-Silva, S.J. Goldfless, M. Dao, J.C. Niles, S. Suresh and J. Han, "A microfabricated deformability-based flow cytometer with application to malaria," Lab on a Chip, 11 (2011) 1065-1073.

A. Singh, L. Tang, M. Dao, L. Lu and S. Suresh, "Fracture toughness and fatigue crack growth characteristics of nanotwinned copper," Acta Materialia, 59 (2011) 2437-2446.

D.J. Quinn, I. Pivkin, S.Y. Wong, K.-H. Chiam, M. Dao, G.E. Karniadakis and S. Suresh, "Combined simulation and experimental study of large deformation of red blood cells in microfluidic systems," Annals of Biomedical Engineering, 39 (2011) 1041-1050. (See supplementary materials.)

H. Yao, M. Dao, D. Carnelli, K. Tai and C. Ortiz, "Size-dependent heterogeneity benefits the mechanical performance of bone," J. Mech. Phys. Solids, 59 (2011) 64-74.

S.C. Bellemare, M. Dao and S. Suresh, "A new method for evaluating the plastic properties of materials through instrumented frictional sliding tests," Acta Materialia, 58 (2010) 6385-6392.

M. Diez-Silva, M. Dao, J. Han, C.-T. Lim and S. Suresh, "Shape and Biomechanical Characteristics of Human Red Blood Cells in Health and Disease," MRS Bulletin, 35 (2010) 382-388. (See =>MRS Bulletin Cover Image.)

H. Yao, M. Dao, T. Imholt, J. Huang, K. Wheeler, A. Bonilla, S. Suresh and C. Ortiz, "Protection mechanisms of the iron-plated armor of a deep-sea hydrothermal vent gastropod," Proc. Natl. Acad. Sci. USA, 107 (2010) 987-992. See supplementary materials. (See =>MIT News Report.)

P. Gu, B.K. Kad and M. Dao, "A modified model for deformation via partial dislocations and stacking faults at the nanoscale," Scripta Materialia, 62 (2010) 361-364.

L. Lu, T. Zhu, Y.F. Shen, M. Dao, K. Lu and S. Suresh, "Stress relaxation and the structure size-dependence of plastic deformation in nano-twinned copper," Acta Materialia, 57 (2009) 5165-5173.

P. Gu, M. Dao and R.J. Asaro, "Structural stability of polymer matrix composite panels in fire," Marine Structures, 22 (2009) 354-372.

L. Lu, M. Dao, T. Zhu and J. Li, "Size dependence of rate-controlling deformation mechanisms in nanotwinned copper," Scripta Materialia (Viewpoint Paper), 60 (2009) 1062-1066.

A. Prasad, M. Dao and S. Suresh, "Steady-state frictional sliding contact on surfaces of plastically graded materials," Acta Materialia, 57 (2009) 511-524.

A. Jerusalem, M. Dao, S. Suresh and R. Radovitzky, "Three-dimensional model of strength and ductility of polycrystalline copper containing nanoscale twins," Acta Materialia, 56 (2008) 4647-4657.

H. Takagi, M. Dao and M. Fujiwara, "Analysis on Pseudo-Steady Indentation Creep," Acta Mechanica Solida Sinica, 21 (2008) 283-288.

T.-S. Park, M. Dao, S. Suresh, A.J. Rosakis, D. Pantuso and S. Shankar, "Some Practical Issues of Curvature and Thermal Stress in Realistic Multilevel Metal Interconnect Structures," J. Elec. Mater., 37 (2008) 777-791.

I.S. Choi, M. Dao and S. Suresh, "Mechanics of Indentation of Plastically Graded Materials: I. Analysis," J. Mech. Phys. Solids 56 (2008) 157-171.

I.S. Choi, A.J. Detor, R. Schwaiger, M. Dao, C.A. Schuh and S. Suresh, "Mechanics of Indentation of Plastically Graded Materials: II. Experiments on Nanocrystalline Alloys with Grain-Size Gradients," J. Mech. Phys. Solids 56 (2008) 172-183.

S. Bellemare, M. Dao and S. Suresh, "Effects of Mechanical Properties and Surface Friction on Elasto-Plastic Sliding Contact," Mech. Mater. 40 (2008) 206-219.

K. Tai, M. Dao, S. Suresh, A. Palazoglu and C. Ortiz, "Nanoscale Heterogeneity Promotes Energy Dissipation in Bone," Nature Materials, 6 (2007) 454-462. See supplementary materials.

M. Dao, L. Lu, R.J. Asaro, J.T.M. De Hosson and E. Ma, "Toward a quantitative understanding of mechanical behavior of nanocrystalline metals," Acta Materialia (Overview No. 143), 55 (2007) 4041-4065.

J.P. Mills, M. Diez-Silva, D.J. Quinn, M. Dao, M.J. Lang, K.S.W. Tan, C.T. Lim, G. Milon, P.H. David, O. Mercereau-Puijalon, S. Bonnefoy and S. Suresh, "Effect of plasmodial RESA protein on deformability of human red blood cells harboring Plasmodium falciparum," Proc. Natl. Acad. Sci. USA, 104 (2007) 9213-9217. (See =>MIT News Report.)

J. Li, G. Lykotrafitis, M. Dao and S. Suresh, "Cytoskeletal dynamics of human erythrocyte," Proc. Natl. Acad. Sci. USA, 104 (2007) 4937-4942. See supplementary materials. (See =>MIT News Report & =>MIT Tech Talk Article & =>MRS Materials360.)

A. Gouldstone, N. Chollacoop, M. Dao, J. Li, A. M. Minor and Y.-L. Shen, "Indentation across size scales and disciplines: Recent developments in experimentation and modeling," Acta Materialia (Overview No. 142), 55 (2007) 4015-4039.

Y.P. Cao, M. Dao and J. Lu, "A precise correcting method for the study of the superhard material using nanoindentation tests," J. Mater. Res., 22 (2007) 1255-1264.

S. Bellemare, M. Dao and S. Suresh, "The frictional sliding response of elasto-plastic materials in contact with a conical indenter," International Journal of Solids and Structures, 44 (2007) 1970-1989.

M. Dao, L. Lu, Y.F. Shen and S. Suresh, "Strength, Strain-Rate Sensitivity and Ductility of Copper with Nano-Scale Twins," Acta Materialia, 54 (2006) 5421-5432.

M. Dao, J. Li and S. Suresh, "Molecularly Based Analysis of Deformation of Spectrin Network and Human Erythrocyte," Materials Science and Engineering C, 26 (2006) 1232-1244.

H. Takagi, M. Dao, M. Fujiwara and M. Otsuka, "Creep Characterization of Aluminum-Magnesium Solid-Solution Alloy through Self-Similar Microindentation," Materials Transactions, JIM, 47 (2006) 2006-2014. (2006 Japan Institute of Metals Best Paper Award) (==> Access Japanese Version Here.)

Y.F. Shen, L. Lu, M. Dao and S. Suresh, "Strain rate sensitivity of Cu with nanoscale twins," Scripta Materialia, 55 (2006) 319-322.

H. Takagi, M. Dao and M. Fujiwara, "Experimental and computational study on the load-jump tests of Al-Mg solid-solution alloy using instrumented indentation technique," Mater. Sci. Eng. A, 423 (2006) 24-27.

J. Li, M. Dao, C.T. Lim and S. Suresh, "Spectrin-Level Modeling of the Cytoskeleton and Optical Tweezers Stretching of the Erythrocyte," Biophysical Journal, 88 (2005) 3707-3719. See supplementary materials.

J. Mills, L. Qie, M. Dao, K. S.W. Tan, C. T. Lim and S. Suresh, "Continuous force-displacement relationships for the human red blood cell at different erythrocytic developmental stages of Plasmodium falciparum malaria parasite," Mater. Res. Soc. Symp. Proc., 844, Y7.8, 2005. (Outstanding Paper Award)

L. Lu, R. Schwaiger, Z.W. Shan, M. Dao, K. Lu and S. Suresh, "Nano-sized Twins Induce High Rate Sensitivity of Flow Stress in Pure Copper," Acta Materialia, 53 (2005) 2169-2179.

S. Suresh, J. Spatz, J.P. Mills, A. Micoulet, M. Dao, C.T. Lim, M. Beil and T. Seufferlein, "Connections between single cell biomechanics and human disease states: gastrointestinal cancer and malaria," Acta Biomaterialia, 1 (2005) 15-30. See supplementary materials. (See =>MIT News Report & =>MIT Tech Talk Article.)

J.P. Mills, L. Qie, M. Dao, C.T. Lim and S. Suresh, "Nonlinear elastic and viscoelastic deformation of the human red blood cell with optical tweezers," Mech Chem Biosystems, 1 (2004) 169-180.

C.T. Lim, M. Dao, S. Suresh, C.H. Sow and K.T. Chew, "Large deformation of living cells using laser traps," Acta Materialia, 52 (2004) 1837-1845.


• C.T. Lim, M. Dao, S. Suresh, C.H. Sow and K.T. Chew, "Corrigendum to Large deformation of living cells using laser traps", Acta Materialia, 52 (2004) 4065-4066.

M. Dao, C.T. Lim and S. Suresh, "Mechanics of the human red blood cell deformed by optical tweezers," J. Mech. Phys. Solids, 51 (2003) 2259-2280. See also the Erratum.

H. Takagi, M. Dao, M. Fujiwara and M. Otsuka, "Experimental and Computational Creep Characterization of Al-Mg Solid Solution Alloy through Instrumented Indentation," Phil. Mag., 83 (2003) 3959-3976. See also the Errata.

R. Schwaiger, B. Moser, M. Dao, N. Chollacoop and S. Suresh, "Some Critical Experiments on the Strain-Rate Sensitivity of Nanocrystalline Nickel," Acta Materialia, 51 (2003) 5159-5172.

N. Chollacoop, M. Dao and S. Suresh, "Depth-Sensing Instrumented Indentation with Dual Sharp Indenters," Acta Materialia, 51 (2003) 3713-3729.

M. Dao, N. Chollacoop, K.J. Van Vliet, T.A. Venkatesh and S. Suresh, "Computational Modeling of the Forward and Reverse Problems in Instrumented Sharp Indentation," Acta Materialia, 49 (2001) 3899-3918.

R. Vaidyanathan, M. Dao, G. Ravichandran and S. Suresh, "Study of Mechanical Deformation in Bulk Metallic Glass through Instrumented Indentation," Acta Materialia, 49 (2001) 3781-3789.

M. Dao and M. Li, "A Micromechanics Study on Strain Localization Induced Fracture Initiation in Bending using Crystal Plasticity Models," Phil. Mag. A, 81 (2001) 1997-2020.

P. Gu, M. Dao and R. J. Asaro, "A Simplified Method for Calculating the Crack-Tip Field of Functionally Graded Materials Using the Domain Integral," ASME J. Appl. Mech., 66 (1999) 101-108.

M. Dao and R. J. Asaro, "A Study on Failure Prediction and Design Criteria for Fiber Composites under Fire Degradation," Comp. A, 30 (1999) 123-131.

M. Dao, R. J. Asaro and D. Alley, "Fire Degradation and Failure Prediction of Fiber Composites Under Compressive Loading," U.S. Coast Guard position paper vis-a-vis the International Maritime Organization (IMO), 1998.

M. Dao, R. J. Asaro and R. J. Sebring, "Interface Instability in the Bulk Processing of 2223 BSCCO Powders," Phil. Mag. A, 78 (1998) 857-877.

M. Dao, P. Gu, A. Maewal and R. J. Asaro, "A Micromechanical Study of Residual Stresses in Functionally Graded Materials," Acta Materialia, 45 (1997) 3265-3276.

M. Dao, B. K. Kad and R. J. Asaro, "Mechanism of Intense Shear Failure in Ni3Al Single Crystals," Phil. Mag. A, 75 (1997) 443-459.

M. Dao, B. K. Kad and R. J. Asaro, "Deformation and Fracture under Compressive Loading in Lamellar TiAl Microstructures," Phil. Mag. A, 74 (1996) 569-591.

M. Dao, B. J. Lee and R. J. Asaro, "Non-Schmid Effects on the Behavior of Polycrystals -- with Applications to Ni3Al," Metall. Trans. A, 27 (1996) 81-99.

M. Dao and R. J. Asaro, "Loacalized Deformation Modes and Non-Schmid Effects in Crystalline Solids. Part I. Critical Conditions of Localization," Mech. Mater. A, 23 (1996) 71-102.

M. Dao and R. J. Asaro, "Loacalized Deformation Modes and Non-Schmid Effects in Crystalline Solids. Part II. Deformation Patterns," Mech. Mater. A, 23 (1996) 103-132.

M. Dao and R. J. Asaro, "On the Critical Conditions of Kink Band Formation in Fiber Composites with Ductile Matrix," Scripta Materialia, 34 (1996) 1771-1777.

B. K. Kad, M. Dao and R. J. Asaro, "Numerical Simulations of Plastic Deformation and Fracture Effects in Two Phase gamma-TiAl + alpha2-Ti3Al Lamellar Microstructures," Phil. Mag. A, 71 (1995) 567-604.

Education

• Ph.D. in Materials Science, Univ. of California at San Diego, 1994
• M.S. in Materials Science, Univ. of California at San Diego, 1991
• B.S. in Eng. Mechanics, Shanghai Jiao Tong University (China), 1989

Honors and Awards

• Singapore Research Professor of Bioengineering and Infectious Disease, 2012, MIT
• No. 1 among Top 25 Hottest Articles, April-June 2007, Acta Materialia
• Best Paper Award, 2006, Materials Transaction, Japan Institute of Metals
• Best Poster Award, 1994, MRS Symposium on High Temperature Ordered Intermetallics Boston, Massachusetts.
• Best Graduating Student Award, 1989, Shanghai Jiao Tong Univ.
• Chinese National Math Competition, 2nd Price, 1984, China.