Postdoctoral Associate, Parsons Laboratory, Department of Civil and Environmental Engineering

15 Vassar Street, Bldg 48-108, Cambridge, MA 02139. Massachusetts Institute of Technology

My basic motivation is to gain a systems level understanding of microbial communities, from the level of genes and their patterns of transmission to the level of ecological interactions. In my research I integrate population genomics and high-throughput reconstruction of microbial interaction networks to understand the ecological and evolutionary processes that shape natural populations and communities.

Publications

O.X. Cordero, L Ventouras, E.F. DeLong and M.F. Polz. (2012) Public Good Dynamics Drive Evolution of Iron Acquisition Strategies in Natural Bacterioplankton Populations. PNAS, 109(49):20059-64

O.X. Cordero, H. Windschutte, B.C. Kirkup, S. Proehl, F.A. Hussain, F. Le Roux, T. Mincer and M. F. Polz. (2012) Ecological populations of bacteria act as units of antibiotic production and resistance. Science. Vol. 337 no. 6099 pp.1228-31

B.J Shapiro, J. Friedman, O.X. Cordero, S. Preheim, D. Hunt, S. Timberlake, M.F. Polz, and E.J. Alm. (2012) Population genomics of early events in the ecological differentiation of bacteria. Science. Vol. 336 no. 6077 pp. 48-51

CS Smillie, MB Smith, J Friedman, OX Cordero, LA David and EJ Alm. (2011) Ecology drives a global network of gene exchange connecting the human microbiome. Nature. 480, 241–244

Y Boucher, OX Cordero, A Takemura, DE. Hunt, K Schliep, E Bapteste, P Lopez, CL Tarrd, and MF Polz. (2011) Local Mobile Gene Pools Rapidly Cross Species Boundaries To Create Endemicity within Global Vibrio cholerae Populations. Mbio.

L Wang, S Chen, KL Vergin, SJ Giovannoni, SW Chan, MS DeMott, K Taghizadeh, OX Cordero, M Cutler, S Timberlake, EJ Alm, MF Polz, J Pinhassi, Z Deng, PC Dedon. (2011) DNA phosphorothioation is widespread and quantized in bacterial genomes. PNAS.

OX Cordero and P Hogeweg. (2009) The impact of long-distance horizontal gene transfer on prokaryotic genome size. PNAS.

OX Cordero and P Hogeweg (2009) The consequences of base pair composition biases for regulatory network organization in prokaryotes. Mol. Biol. Evol. 26(10):2171–2173

OX Cordero and P Hogeweg (2009) Regulome size in prokaryotes: universality and lineage specific variations. Trends in Genetics. Vol. 25 Pages 285-286

OX Cordero, B Snel and P Hogeweg (2008) Coevolution of gene families in prokaryotes. Genome Research. 18(3):462-8.

OX Cordero and P Hogeweg (2007) Large changes in regulome size herald the main prokaryotic lineages. Cordero and Hogeweg. Trends in Genetics. Vol. 23 pp. 488–493

OX Cordero and P Hogeweg (2006) Feed forward loop circuits as a side effect of genome mutational dynamics. Cordero and Hogeweg. Molecular Biology and Evolution. 23(10):1931-1936.