Publications

If you do not have journal access for any of the papers below, send me an email and I will gladly provide a copy of the manuscript.


2022 Lo, C.L.; Joaquin, D.L.; Moya, D.A.; Ramos, A.R.; Kastner, D.W.; White, S.M.; Christensen, B.L.; Naglich, J.G.; Degnen, W.J.; Castle, S.L.; “Synthesis and evaluation of potent yaku'amide analogs.” Chemical Science. 13(7), 1899-1905 2022. [cover]
Flores, A.D; Kastner, D.W.; Du, Y.; Narayanamoorthy, M.; Shen, Y.; Cai, W.; Vennelakanti, V.; Zill, A.A.; Dell, L.B.; Zhai, R.; Kulik, H.J.; Zhang, W.; “Probing the mechanism of isonitrile formation by a non-heme iron(II)-dependent oxidase/decarboxylase” Journal of the American Chemical Society 144(13), 5893-5901 2022. [cover]
Nandy, A.; Terrones, G.; Arunachalam, N.; Duan, C.; Kastner, D.W.; Kulik, H.J.; “MOFSimplify, machine learning models with extracted stability data of three thousand metal–organic frameworks” Scientific Data 9(74) 2022. [feature] [MIT] [mirage] [nanowerk] [phys.org] [technology.org] [ireland]
Nazemi, A.; Steeves, A.H.; Kastner, D.W.; Kulik, H.J.; “Influence of the Greater Protein Environment on the Electrostatic Potential in Metalloenzyme Active Sites: The Case of Formate Dehydrogenase” Journal of the American Chemical Society 126(22), 2069-4079 2022. [cover]
2021 Olsen, R.O.; Ireland, A.S.; Kastner, D.W.; Groves, S.M.; Spainhower, K.B.; Pozo, K.; Kelenis, D.P.; Whitney, C.P.; Guthrie, M.R.; Wait, S.J.; Soltero, D.; Witt, B.L.; Quaranta, V.; Johnson, J.E.; Oliver, T.G.; “ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer.” Genes & Development. 35, 847-869 2021. [preprint]
2020 Ireland, A.S.; Micinski, A.M.; Kastner, D.W.; Guo, B.; Wait, S.J.; Spainhower, K.B.; Conley, C.C.; Chen, O.S.; Guthrie, M.R.; Soltero, D.; Qiao, Y.; Huang, X.; Tarapcsak, S.; Devarakonda, S.; Chalishazar, M.D.; Gertz, J.; Moser, J.C.; Marth, G.; Puri, S.; Witt, B.L.; Spike, B.T.; Oliver, T.G. “MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate.” Cancer Cell. 1(38), 60-78 2020. [preview] [spotlight]
Joaquin, D., Lee, M., Kastner, D.W., Singh, J., Shardon, D., Damstedt, G., Castle, S. “Impact of Dehydroamino Acids on the Structure and Stability of Incipient 310-Helical Peptides” The Journal of Organic Chemistry 3(85), 1601-1613 2020. [preprint]
2019 Morris, D. L., Kastner, D. W., Johnson, S., Strub, M., He, Y., Bleck, C. K., Lee, D., Tjandra, N. “Humanin induces conformational changes in the apoptosis regulator BAX and sequesters it into fibers, preventing mitochondrial outer-membrane permeabilization” Journal of Biological Chemistry 50(294), 19055-19065 2019.
Kastner, D. W. “Computational Modelling of Peptides Containing Non-standard Amino Acids” Undergraduate Honors Thesis, 2019.
Kastner, D. W. “The Ultimate Triumph of Truth,” BYU Speeches , University Commencement, 2019. [print] [video] [BYU News] [Napa Register]
2018 Ashraf, N. M., Krishnagopal, A., Hussain, A., Kastner, D. W., Mahmoud, A., Sayed, M., Mok, Y., Swaminathan, K., Zeeshan, N. “Engineering of serine protease for improved thermostability and catalytic activity using rational design” Int. J. Biol. Macromol. 126(229-237), 2019.
Kastner, D. W., Castle, S.L. “ONIOM(DFT:MM) study of yaku'amide A and analogues” Journal of Undergraduate Research ORCA, 2018.
2017 Jalan, A., Kastner, D. W., Webber, K. G. I., Smith, M., Price, J. L., Castle, S. L. “Bulky Dehydroamino Acids Enhance Proteolytic Stability and Folding in β-Hairpin Peptides.” Org. Lett. 19(19), 5190-5193 2018. [poster]
Ashraf, N. M., Imran, K., Kastner, D. W., Ikram, K., Mushtaq, A., Hussain, A., Zeeshan. N. “Potential involvement of mi-RNA 574-3p in progression of prostate cancer: A bioinformatic study.” Mol. Cell Probes. 36(11), 21-28 2017.