Above is a short movie that shows how NeuroRighter can be used to clamp the population firing rate of a dissociated cortical culture, grown on a microelectrode array. The first 30 seconds of the movie shows the network engaged in spontaneous activity. Starting at 30 seconds, a feedback controller is engaged and the firing rate is clamped at 3 Hz/neuron using spatially distributed electrical stimulation. The top plot shows the firing rate of a neuron in the culture. The middle plot is a rastergram showing the spiking patterns of individual neurons (black dots) and electrical stimuli (red dots). The bottom plot is a spatial activity histogram, with each (x,y) coordinate indexing a particular electrode, and corresponding height/color indicating the detected firing rate on that electrode.