Renato Umeton, Ph.D.

Data Science, Machine Learning, Optimization, Biostatistics.

 

PublicationsYear
A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials
C Eleuteri, S Olla, C Veroni, R Umeton, R Mechelli, S Romano, ...
Nature Scientific Reports 7, 45780, 2017
 2017
Portable medical device and method for quantitative retinal image analysis through a smartphone
C Stamile, R Umeton, M Cavallari, F Calimeri, F Orzi, , F Orzi
US Patent 9,468,377, 2016
 2016
Gene-environment interaction study in multiple sclerosis using a" candidate-interactome" approach
R Mechelli, R Umeton, Imsgc-Wtccc, G Ristori, M Salvetti
MULTIPLE SCLEROSIS JOURNAL 22, 191-192, 2016
 2016
Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study
MC Buscarinu, B Cerasoli, V Annibali, C Policano, L Lionetto, M Capi, ...
Multiple Sclerosis Journal, 1352458516652498, 2016
82016
Novel method for automated analysis of retinal images: results in subjects with hypertensive retinopathy and CADASIL
M Cavallari, C Stamile, R Umeton, F Calimeri, F Orzi
BioMed research international 2015, 2015
62015
IFN-β and multiple sclerosis: from etiology to therapy and back
V Annibali, R Mechelli, S Romano, MC Buscarinu, A Fornasiero, ...
Cytokine & growth factor reviews 26 (2), 221-228, 2015
142015
Epstein-Barr virus genetic variants are associated with multiple sclerosis.
R Mechelli, C Manzari, C Policano, A Annese, E Picardi, R Umeton, ...
Neurology 31 (84), 1362-8, 2015
162015
B cell IRF1 pathway is dysregulated in multiple sclerosis
V Annibali, R Umeton, A Palermo, MC Buscarinu, C Policano, R Mechelli, ...
Journal of Neuroimmunology 275 (1), 1, 2014
 2014
Noise in multiple sclerosis: unwanted and necessary
I Bordi, VAG Ricigliano, R Umeton, G Ristori, F Grassi, A Crisanti, ...
Annals of clinical and translational neurology 1 (7), 502-511, 2014
22014
Epstein barr virus genotipic variants and uses thereof as risk predictors, biomarkers and therapeutic targets in multiple sclerosis
G Ristori, R Mechelli, M Salvetti, C Policano, R Umeton, , R Umeton
US Patent App. 14/782,556, 2014
 2014
Drug repositioning and computational analysis for myelin disease regenerative therapies
C Eleuteri, C Veroni, M Floris, S Olla, R Umeton, G Ristori, V Annibali, ...
MULTIPLE SCLEROSIS JOURNAL 19 (11), 163-163, 2013
 2013
Contribution of genome-wide association studies to scientific research: a pragmatic approach to evaluate their impact
VAG Ricigliano, R Umeton, L Germinario, E Alma, M Briani, N Di Segni, ...
PloS one 8 (8), e71198, 2013
72013
In silico modeling of shear-stress-induced nitric oxide production in endothelial cells through systems biology
A Koo, D Nordsletten, R Umeton, et al.
Biophysical journal 104 (10), 2295-2306, 2013
172013
A “candidate-interactome” aggregate analysis of genome-wide association data in multiple sclerosis
R Mechelli, R Umeton, C Policano, V Annibali, G Coarelli, VAG Ricigliano, ...
PLoS One 8 (5), e63300, 2013
182013
Efficient behavior of photosynthetic organelles via Pareto optimality, identifiability, and sensitivity analysis
G Carapezza, R Umeton, J Costanza, C Angione, G Stracquadanio, ...
ACS synthetic biology 2 (5), 274-288, 2013
82013
A mechanistic, stochastic model helps understand multiple sclerosis course and pathogenesis
I Bordi, R Umeton, VAG Ricigliano, V Annibali, R Mechelli, G Ristori, ...
International journal of genomics 2013, 2013
82013
Automated analysis of retinal photographs: results in subjects with hypertensive retinopathy and CADASIL
M Cavallari, C Stamile, R Umeton, F Orzi
NEUROLOGY 80, 2013
12013
Automated Analysis of Retinal Photographs: Results in Subjects with Hypertensive Retinopathy and CADASIL (P06. 009)
M Cavallari, C Stamile, R Umeton, F Orzi
Neurology 80 (7 Supplement), P06. 009-P06. 009, 2013
 2013
Automated Analysis of Retinal Photographs: Results in Subjects with Hypertensive Retinopathy and CADASIL (IN4-1.001)
M Cavallari, C Stamile, R Umeton, F Orzi
Neurology 80 (7 Supplement), IN4-1.001-IN4-1.001, 2013
 2013
A ‘‘Candidate-Interactome’’Aggregate Analysis of Genome-Wide Association Data
R Mechelli, R Umeton, C Policano, V Annibali, G Coarelli
 2013
Transciptome of B lymphocytes in multiple sclerosis
V Annibali, R Umeton, A Annese, A Palermo, R Mechelli, C Policano, ...
JOURNAL OF NEUROIMMUNOLOGY 253 (1-2), 9-9, 2012
 2012
New enhancers of endogenous remyelination: an extensive in vitro and ex vivo screening
C Eleuteri, C Veroni, R Umeton, V Annibali, G Ristori, M Salvetti, C Agresti
28th Congress of the European Committee for Treatment and Research in ..., 2012
22012
OREMPdb: a semantic dictionary of computational pathway models
R Umeton, G Nicosia, CF Dewey
BMC bioinformatics 13 (4), S6, 2012
72012
Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood
R Calabrese, M Zampieri, R Mechelli, V Annibali, T Guastafierro, ...
Multiple Sclerosis Journal 18 (3), 299-304, 2012
302012
Identification of sensitive enzymes in the photosynthetic carbon metabolism
R Umeton, G Stracquadanio, A Papini, J Costanza, P Lio, G Nicosia
Advances in Systems Biology, 441-459, 2012
42012
Design of robust metabolic pathways
R Umeton, G Stracquadanio, A Sorathiya, P Liò, A Papini, G Nicosia
Proceedings of the 48th Design Automation Conference, 747-752, 2011
102011
Semantic Queries for Biomedical Pathways
R Umeton, G Nicosia, CF Dewey Jr
10th Workshop on Process Algebra and Stochastically Timed Activities (PASTA ..., 2011
 2011
Multi-scale Mathematical Modeling to Support Drug Development
DA Nordsletten, BY Yankama, R Umeton, et al.
IEEE Transactions on Biomedical Engineering, 2011
42011
Large scale agent-based modeling of the humoral and cellular immune response
G Stracquadanio, R Umeton, J Costanza, V Annibali, R Mechelli, ...
International Conference on Artificial Immune Systems (ICARIS 2011), 15-29, 2011
12011
Key Enzymes for the Optimization of CO 2 Uptake and Nitrogen Consumption in the C 3 Photosynthetic Carbon Metabolism
A Papini, G Nicosia, G Stracquadanio, P Lio, R Umeton
Journal of Biotechnology 150, 525-526, 2010
22010
ORES-2010 Ontology Repositories and Editors for the Semantic Web
M d'Aquin, AG Castro, C Lange, K Viljanen
32010
Analysis and optimization of c3 photosynthetic carbon metabolism
G Stracquadanio, R Umeton, A Papini, P Liò, G Nicosia
BioInformatics and BioEngineering (BIBE), 2010 IEEE International Conference ..., 2010
92010
A Cross-Format Framework for Consistent Information Integration among Molecular Pathways and Ontologies
R Umeton, B Yankama, G Nicosia, CF Dewey
6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore ..., 2010
22010
OREMP: Ontology Reasoning Engine for Molecular Pathways
R Umeton, B Yankama, G Nicosia, CF Dewey Jr
1st International Workshop on Ontology Repositories and Editors for the ..., 2010
12010
Highway traffic model based on cellular automata: Preliminary simulation results with congestion pricing considerations
S Di Gregorio, R Umeton, A Bicocchi, A Evangelisti, MC Gonzalez
20th European Modeling and Simulation Symposium, EMSS 2008, 17-19 September ..., 2008
22008
A CELLULAR AUTOMATA MODEL FOR HIGHWAY TRAFFIC WITH PRELIMINARY RESULTS
S Di Gregorio, R Umeton, A Bicocchi, A Evangelisti
Artificial Life and Evolutionary Computation: Proceedings of Wivace 2008, 235, 2008
 2008
“ADMISSIBLE METHOD FOR IMPROVED GENETIC SEARCH IN CELLULAR AUTOMATA MODEL (AMMISCA)”: A STRATEGY IN GENETIC CALIBRATION-PRELIMINARY RESULTS
R UMETON, S DI GREGORIO
Artificial Life and Evolutionary Computation: Proceedings of Wivace 2008, 99, 2008
 2008
Efficient Behavior of Photosynthetic Organelles via Pareto Optimality, Identifiability and Sensitivity Analysis-Appendix Supplementary Information
G Carapezza, R Umeton, J Costanza, C Angione, G Stracquadanio, ...
 
Modeling and Optimization of Efficient Photosynthetic Organelles-Appendix Supplementary Information
G Carapezza, R Umeton, J Costanza, C Angione, G Stracquadanio, ...
 
OREMPdb: a Semantic Dictionary of Runnable Biological Circuits
R Umeton, G Nicosia, CF Dewey Jr