Matthew Eaton

Kellis Lab, Computational Biology, MIT.

Since June 2011, I have been working as a postdoctoral researcher under the guidance of Manolis Kellis in the Computer Science and Artificial Intelligence Lab of MIT and the Broad Institute. I am currenty working on high-throughput epigenetic analysis and its applications to human disease. I did my Ph.D. at Duke University with David MacAlpine in the Program in Computational Biology and Bioinformatics and the Pharmacology and Cancer Biology Department. With Dave I focused on a computational analysis of the chromatin determinants of the eukaryotic replication program, and graduated in May 2011.


Publications

(* denotes co-first author)

ENCODE consortium, et al. "An integrated encyclopedia of DNA elements in the human genome." Nature 489(7414):57-74 (September 2012)

Sher, Noa, George W. Bell, Li Sharon, Jared Nordman, Thomas Eng, Matthew L. Eaton, David M. MacAlpine, Terry L. Orr-Weaver. "Developmental control of gene copy number by repression of replication initiation and fork progression." Genes & Development Epub ahead of print (Nov 29, 2011).

Eaton, Matthew L, Joseph A Prinz, Heather K Macalpine, George Tretyakov, Peter V Kharchenko, and David M Macalpine. "Chromatin signatures of the Drosophila replication program." Genome Research (Feb, 2011): 21(2), 164-74.  

modENCODE consortium, Sushmita Roy*, Jason Ernst*, Peter V Kharchenko*, Pouya Kheradpour*, Nicolas Negre*, Matthew L Eaton*, Jane M Landolin*, et al. "Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE." Science (New York, N.Y.) (December 22, 2010).  

Nègre N*, Brown CD*, Ma L*, Bristow CA*, Miller SW*, Wagner U*, Kheradpour P, Eaton ML, et al. "A cis-regulatory map of the Drosophila genome." Nature 471, no. 7339 (March 2011): 527-31.

Dwyer, Mary A, James Joseph, Hilary E Wade, Matthew L Eaton, Rebecca S Kunder, Dmitri Kazmin, Ching-Yi Chang, and Donald P McDonnell. “WNT11 expression is induced by ERR{alpha} and {beta}-catenin and acts in an autocrine manner to increase cancer cell migration.” Cancer Research (September 24, 2010).  

Eaton, Matthew L*, Kyriaki Galani*, Sukhyun Kang, Stephen P Bell, and David M MacAlpine. “Conserved nucleosome positioning defines replication origins.” Genes & Development 24, no. 8 (April 15, 2010): 748-753.  

Müller, Philipp, Sookhee Park, Erika Shor, Dana J Huebert, Christopher L Warren, Aseem Z Ansari, Michael Weinreich, Matthew L Eaton, David M MacAlpine, and Catherine A Fox. “The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin.” Genes & Development 24, no. 13 (July 1, 2010): 1418-1433.  

Wade, Hilary E, Sakiko Kobayashi, Matthew L Eaton, Michelle S Jansen, Edward K Lobenhofer, Mathieu Lupien, Timothy R Geistlinger, et al. “Multimodal regulation of E2F1 gene expression by progestins.” Molecular and Cellular Biology 30, no. 8 (April 2010): 1866-1877.  

Weir, Michael, Matthew Eaton, and Michael Rice. “Challenging the spliceosome machine.” Genome Biology 7, no. 1 (2006): R3.  


Note: this list was produced by Zotero.


Matthew Eaton
Postdoctoral Associate
Computational Biology
Kellis Lab
MIT & Broad Institute
CSAIL - Stata Center - 32-D514
mleaton (at) MIT (dot) edu
View Matthew Eaton's profile on LinkedIn