Joshua A. Weinstein
jwein at broadinstitute dot org
Broad Institute/MIT, Post-doctoral Associate
LSRF, Simons Fellow

Stanford University, PhD Biophysics 2012
University of Pennsylvania, BA Physics/Biophysics 2006

Research interests
DNA-based technologies
Statistical mechanics of multicellular systems
Dimensionality reduction and data visualization

Selected publications

  1. Weinstein JA, Regev A, Zhang F. "DNA microscopy: Optics-free spatio-genetic imaging by a stand-alone chemical reaction." Preprint 2018 Nov 19. bioRxiv 471219; doi:
  2. Vollmers C, Sit RV, Weinstein JA, Dekker CL, Quake SR. "Genetic measurement of memory B-cell recall using antibody repertoire sequencing." Proc Natl Acad Sci USA. 2013 Jul 29; doi:10.1073/pnas.1312146110.
  3. Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. "DNA targeting specificity of RNA-guided Cas9 nucleases." Nat Biotech. 2013 Jul 21; doi:10.1038/nbt.2647.
  4. Weinstein JA, Zeng X, Chien YC, Quake SR. "Correlation of gene expression and genome mutation in single B-cells." PLoS ONE. 2013 Jun 28; 8(6): e67624.
  5. Jiang N*, He J*, Weinstein JA*, Penland L, Sasaki S, He XS, Dekker CL, Zheng NY, Huang M, Sullivan M, Wilson PC, Greenberg HB, Davis MM, Fisher DS, Quake SR. "Lineage structure of the human antibody repertoire in response to influenza vaccination." Sci Transl Med. 2013 Feb 6;5(171):171ra19
  6. Jiang N*, Weinstein JA*, Penland L, White RA 3rd, Fisher DS, Quake SR. "Determinism and stochasticity during maturation of the zebrafish antibody repertoire." Proc Natl Acad Sci USA. 2011 Mar 29;108(13):5348-53.
  7. Weinstein JA*, Jiang N*, White RA 3rd, Fisher DS, Quake SR. "High-throughput sequencing of the zebrafish antibody repertoire." Science. 2009 May 8;324(5928):807-10.

For a full list of publications, see CV.