At the Physics Research Laboratory, an improved area sensing rotate-translate PET instrument, PC-II, was constructed 1971-1976 and the tomographic images obtained using PC-I and PC-II were widely disseminated at meetings and in publications (Figures 6-14) (Chesler et al 1973 [25] [26], Brownell et al 1974 [13], Chesler and Riederer 1975 [27], Correia et al 1976 [30], Brownell et al 1976 [14], Hoop et al 1976 [34], Brownell and Cochavi 1978 [15], Brownell et al 1983 [17]).
PC-I was the first device to obtain PET images and, together with PC-II, remained the only PET devices in use for animal and human imaging for almost a decade. A commercial version developed by The Cyclotron Corporation incorporated additional features (Figure 15). (EMI used an iterative algorithm for reconstruction of data from their original machines.) Among those contributing to the early studies were Saadia Cochavi, Wally Ahluwalia, Barney Hoop, John Correia and Nathaniel Alpert.
 |
 |
 |
 |
 |
 |
infused into dog myocardium using PC-I.
corresponding the image on top right, uncorrected
for absorption (left). Same as left with absorption correction
(right).
bone scan using PC-I. AP view shows multiple bone
metastases in the pelvic area, the spine, the ribs, and the calvarium.
The figure at the middle shows the levels where tomographic slices
were reconstructed. Tomographic slices show better assessment of the
location and size of the metastases.
. Lower panel shows 4 tomographic
coronal slices and the arrow points the tumor.
2-fluoro-2-deoxy-D-glucose and PC-II.
), oxygen metabolism (continuous inhalation of 
)
and oxygen
extraction fraction in a rabbit tumor model using PC-II.
