Pathophysiology Guided T-Wave Alternans Measurement - Chapter 7

S.M. Narayan

TWA This page provides supplementary information and relevant links for Chapter 7 in Advanced Methods for ECG Analysis, which is co-edited by Francisco Azuaje and Patrick McSharry, and is published by Artech House. The main URL for this book can be found here, together with ordering information. Much of the software associated with this book can be found here.







7.1 Introduction


7.2 Phenomenology of T-Wave Alternans


7.3 Pathophysiology of T-Wave Alternans


7.4 Measurable Indices of ECG T-Wave Alternans


7.5 Measurement Techniques

7.5.1 Requirements for the Digitized ECG Signal

7.5.2 Short-Term Fourier Transform-Based Methods

7.5.3 Interpretation of Spectral TWA Test Results

7.5.4 Controversies of the STFT Approach

7.5.5 Sign-Change Counting Methods

7.5.6 Nonlinear Filtering Methods

7.6 Tailoring Analysis of TWA to Its Pathophysiology

7.6.1 Current Approaches for Eliciting TWA

7.6.2 Steady-State Rhythms and Stationary TWA

7.6.3 Fluctuating Heart Rates and Nonstationary TWA

7.6.4 Rhythm Discontinuities, Nonstationary TWA, and TWA Phase

7.7 Conclusions