Parsing the Proteome
What is the shortest peptide length that ensures sampling the entire (self) proteome?
In principle all human peptides can be recognized from sequences of length 5-6. Only a few percent of peptides and bound and displayed by MHC.
In principle all human peptides can be recognized from sequences of length 5-6.
Only a few percent of peptides and bound and displayed by MHC.
Next (Thymic Selection) Outline Adaptive Immunity Thymic Selection Proteome segmentation Quorum sensing Affinity Maturation Broadly neutralizing Abs EMF dynamics Summary